1921 Ohio St (5-2) Western

Wk 3 Sat 1 Oct W Ohio Wesleyan 28- 0   (1-0)
Wk 4 Sat 8 Oct L Oberlin 6- 7   (1-1)
Wk 5 Sat 15 Oct W Minnesota 27- 0   (2-1)
Wk 6 Sat 22 Oct W at Michigan 14- 0   (3-1)
Wk 8 Sat 5 Nov W at Chicago 7- 0   (4-1)
Wk 9 Sat 12 Nov W Purdue 28- 0   (5-1)
Wk 10 Sat 19 Nov L Illinois 0- 7   (5-2)