1921 Drake (5-2) MVC

Wk 4 Sat 8 Oct W at William Penn 42- 0   (1-0)
Wk 5 Sat 15 Oct W at Kansas 15- 7   (2-0)
Wk 6 Sat 22 Oct W Cornell-IA 41- 0   (3-0)
Wk 7 Sat 29 Oct L at Missouri 0- 6   (3-1)
Wk 8 Sat 5 Nov L Iowa St 0- 7   (3-2)
Wk 9 Sat 12 Nov W at Morningside 30- 10   (4-2)
Wk 10 Sat 19 Nov W Grinnell 21- 10   (5-2)